SODIUM-TRANSPORT INHIBITORS IN PREGNANCY-INDUCED HYPERTENSION

被引：15

作者：

POSTON, L

机构：

[1] Renal Laboratory, St. Thomas' Hospital and Medical School, London

来源：

CARDIOVASCULAR DRUGS AND THERAPY | 1990年 / 4卷

关键词：

endogenous digoxinlike immunoreactivity; pregnancy-induced hypertension; Sodium transport; sodium transport inhibitor;

D O I：

10.1007/BF02603175

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In blacks and whites of similar socioeconomic background, the incidence of pregnancy-induced hypertension (PIH) is probably the same. In underdeveloped coutries, however, PIH is often a life-threatening complication of pregnancy. Recent theories as to the etiology of PIH include the suggestion that vascular tone may be increased as a result of inhibition of active sodium transport in vascular smooth muscle. This may be the result of an inhibitor of sodium transport present in the serum. The literature concerning the demonstration of endogenous sodium transport inhibitors and endogenous digoxinlike immunoreactivity (EDLI) in PIH is reviewed and discussed. © 1990 Kluwer Academic Publishers.

引用

页码：351 / 356

页数：6

共 42 条

[11]

Poston L., Sewell R.B., Wilkinson S.P., Richardson P.J., Willia R., Clarkson E.M., MacGregor G.A., DeWardener H.E., Evidence for a circulating sodium transport inhibitor in essential hypertension, Br Med J, 282, pp. 847-849, (1981)

[12]

Moreth K., Kuske R., Renner D., Schoner W., Blood pressure in essential hypertension correlates with the concentration of a circulating inhibitor of the sodium pump, Klin Wochenschr, 64, pp. 239-244, (1986)

[13]

Hamlyn J.M., Ringel R.R., Hamilton B.P., Kowarski A.A., Blaustein M.P., Digoxin-like immunoreactivity of a circulating (Na<sup>+</sup>+K<sup>+</sup>)ATPase inhibitor, Nature, 305, (1983)

[14]

Gray H.H., Hilton P.H., Richardson P.J., Effect of serum from patients with essential hypertension on sodium transport in normal leucocoytes, Clin Sci, 70, pp. 583-586, (1986)

[15]

Forrester T.E., Alleyne G.A.O., Leucocyte electrolytes and sodium efflux rate constants in the hypertension of preeclampsia, Clin Sci, 59, pp. 119s-201s, (1980)

[16]

McMurray J.A., Morgan D.B., The sodium content of lymphocytes and mixed leucocytes in pregnancy and pregnancy induced hypertension, Clin Exp Hypertens, 2, pp. 23-30, (1984)

[17]

Seon R., Forrester T., Relationship between leucocyte sodium content and high blood pressure during development and resolution of pre-eclampsia, Clin Sci, 76, pp. 199-203, (1989)

[18]

Forrester T.E., Alleyne G.A.O., Sodium, potassium, and rate constants for sodium efflux in leucocyte from hypertensive Jamaicans, Br Med J, 283, pp. 5-7, (1981)

[19]

Marton I., Spearing G., A factor in pre-eclamptic serum affecting sodium transport across a membrane, J Obstet Gynecol Br Comm, 79, pp. 40-43, (1972)

[20]

Poston L., Morris J.F., Wolfe C.D., Et al., Serum digoxin-like substances in pregnancy-induced hypertension, Clin Sci, 77, pp. 189-194, (1989)

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