NUCLEOTIDE-SEQUENCE PRECEDING AND INCLUDING THE BEGINNING OF THE ILVE GENE OF THE ILVGEDA OPERON OF ESCHERICHIA-COLI-K12

被引：37

作者：

LAWTHER, RP ^{[1
]}

NICHOLS, B ^{[1
]}

ZURAWSKI, G ^{[1
]}

HATFIELD, GW ^{[1
]}

机构：

[1] STANFORD UNIV,DEPT BIOL SCI,STANFORD,CA 94305

来源：

NUCLEIC ACIDS RESEARCH | 1979年 / 7卷 / 08期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1093/nar/7.8.2289

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The DNA sequence of the 570 base pairs that precedes and includes the beginning of the ilvE gene shows no evidence of a leader-attenuator region. Instead, the sequence shows that the ilvE gene is preceded by another structural gene, presumably the normally cryptic ilvG gene. In vitro transcription of two plasmids (pLC26-3 and pRL5) containing the regulatory region of the ilvEDA operon results in the formation of two leader" RNAs. These results are consistent with the suggestion that the ilvEDA operon is regulated by an attenuator mechanism and that the attenuator region lies before the ilvG gene. © 1979 Information Retrieval Limited."

引用

页码：2289 / 2301

页数：13

共 24 条

[1] ILVEDA OPERON OF ESCHERICHIA-COLI-K12 ENCODES ONLY ONE VALINE-ALPHA-KETOGLUTARATE TRANSAMINASE-ACTIVITY [J].