ACETYLENIC AMIDES .1. SYNTHESIS OF N-SUBSTITUTED-2-PROPYNAMIDES

被引：34

作者：

COPPOLA, GM

DAMON, RE

机构：

[1] Sandoz Research Institute, Chemistry Research Department, East Hanover, New Jersey

来源：

SYNTHETIC COMMUNICATIONS | 1993年 / 23卷 / 14期

关键词：

D O I：

10.1080/00397919308009860

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The efficient synthesis of N-substituted-2-propynamides was accomplished by three methods; the reaction of amines with either the N-hydroxysuccinimide ester or mixed anhydride of propiolic acid, or by the interaction of lithiotrimethylsilylacetylene with isocyanates followed by desilation with fluoride.

引用

页码：2003 / 2010

页数：8

共 4 条

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