RAB PROTEINS IN REGULATED EXOCYTOSIS

被引:190
作者
VONMOLLARD, GF
STAHL, B
LI, C
SUDHOF, TC
JAHN, R
机构
[1] YALE UNIV,SCH MED,DEPT CELL BIOL,NEW HAVEN,CT 06510
[2] YALE UNIV,SCH MED,HOWARD HUGHES MED INST,NEW HAVEN,CT 06510
[3] UNIV TEXAS,SW MED CTR,DEPT MOLEC GENET,DALLAS,TX 75235
[4] UNIV TEXAS,SW MED CTR,HOWARD HUGHES MED INST,DALLAS,TX 75235
关键词
D O I
10.1016/0968-0004(94)90278-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Regulated exocytosis is responsible for neuronal communication, hormone secretion, food digestion, control of glucose uptake and many other basic processes. Despite the structural and functional diversity of the cells undergoing regulated exocytosis, all regulated exocytosis involves specialized vesicles that are stored in the cytoplasm and fuse with the plasma membrane in response to a trigger event. Recent evidence suggests that a subset of small GTP-binding proteins, Rab3 and its relatives, participate in the control of regulated exocytosis.
引用
收藏
页码:164 / 168
页数:5
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