AMP-DEAMINASES FROM AVIAN BRAIN AND MUSCLE - CATALYTIC AND IMMUNOLOGICAL DIFFERENCES

被引：18

作者：

HENRY, H

CHILSON, OP

机构：

[1] Department of Biology, Washington University, Saint Louis, MO

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY | 1969年 / 29卷 / 01期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

adenosine-5′-phosphate aminohydrolase; adenylic acid deaminase AMP-deaminase; antibodies effect on brain and muscle deaminase; ATP effect on brain and muscle deaminases; avian enzymes; brain enzymes; enzymes deaminase; Immunoenzymology; immunology; muscle enzymes; nucleotide metabolism; substrate specificity of adenylic acid deaminase; tissue-specific enzymes;

D O I：

10.1016/0010-406X(69)91749-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Purified adenylic acid deaminases from brain and breast muscle of adult chickens have been compared with respect to activation by ATP, substrate specificity and the effect of anti-breast muscle deaminase serum on enzyme activity. 2. 2. Both deaminases are activated by ATP; the effect is most pronounced on the brain enzyme. 3. 3. Although the brain and muscle deaminases will utilize deoxy-AMP, in addition to AMP, as a substrate, the ribonucleotide is deaminated at a faster rate. The brain enzyme is most specific. 4. 4. Rabbit anti-breast muscle deaminase serum strongly inhibits muscle adenylate deaminase but has no effect on the enzyme from brain. © 1969.

引用

页码：301 / &