1,2-DI-O-ACETYL-5-O-BENZOYL-3-DEOXY-3-FLUORO-D-XYLOFURANOSE - A VERSATILE PRECURSOR FOR THE SYNTHESIS OF 3-DEOXY-3-FLUORO-BETA-D-XYLOFURANOSYL NUCLEOSIDES AS POTENTIAL ANTIVIRAL AGENTS

被引：21

作者：

GOSSELIN, G

PUECH, F

GENUDELLAC, C

IMBACH, JL

机构：

[1] Université de Montpellier II, Sciences et Techniques du Languedoc, Laboratoire de Chimie Bio-organique, case courrier, 008, Place Eugene Bataillon

来源：

CARBOHYDRATE RESEARCH | 1993年 / 249卷 / 01期

关键词：

D O I：

10.1016/0008-6215(93)84056-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The title compound has been synthesized from D-xylose for use in the preparation of 3-deoxy-3-fluoro-beta-D-xylofuranosyl nucleoside analogues and their 2-deoxy derivatives, as exemplified in the guanine and thymine series.

引用

页码：1 / 17

页数：17

共 44 条

[1] BASE-CATALYZED DEGRADATIONS OF CARBOHYDRATES .4. FORMATION OF 2,3-ANHYDRO-2-METHOXY ALPHA D-ALLOPYRANOSE DERIVATIVES FROM 3-DEOXY-D-ERYTHRO-HEX-2-ENOPYRANOSES [J].

ASPINALL, GO ;

KING, RR .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1973, 51 (03) :394-401

[2]

AVER A, 1989, NUCLEOS NUCLEOT, V8, P1041

[3]

BARTON DHR, 1975, J CHEM SOC P1, V1, P1574

[4] BRANCHED-CHAIN SUGARS .14. REACTIONS OF SOME GLYCOSULOSE DERIVATIVES WITH DIAZOMETHANE - RING EXPANSION OF GLYCOSULOSE DERIVATIVES [J].

FLAHERTY, B ;

NAHAR, S ;

OVEREND, WG ;

WILLIAMS, NR .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1973, (06) :632-638

[5]

FOSTER A. B., 1967, CARBOHYD RES, V5, P292, DOI 10.1016/S0008-6215(00)80504-2

[6] CYCLOPHOSPHAMIDES FROM AMINOSUGARS AND AMINONUCLEOSIDES [J].

FUJIWARA, AN ;

ACTON, EM ;

GOODMAN, L .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1970, 7 (04) :891-&

[7]

GENU-DELLAC C, 1991, Antiviral Chemistry and Chemotherapy, V2, P83

[8] SYSTEMATIC SYNTHESIS AND ANTIVIRAL EVALUATION OF ALPHA-L-ARABINOFURANOSYL AND 2'-DEOXY-ALPHA-L-ERYTHRO-PENTO-FURANOSYL NUCLEOSIDES OF THE 5 NATURALLY-OCCURRING NUCLEIC-ACID BASES [J].

GENUDELLAC, C ;

GOSSELIN, G ;

PUECH, F ;

HENRY, JC ;

AUBERTIN, AM ;

OBERT, G ;

KIRN, A ;

IMBACH, JL .

NUCLEOSIDES & NUCLEOTIDES, 1991, 10 (06) :1345-1376

[9]

GENUDELLAC C, 1991, CARBOHYD RES, V216, P249

[10] SYSTEMATIC SYNTHESIS AND BIOLOGICAL EVALUATION OF ALPHA-D-LYXOFURANOSYL AND BETA-D-LYXOFURANOSYL NUCLEOSIDES OF THE 5 NATURALLY-OCCURRING NUCLEIC-ACID BASES [J].

GOSSELIN, G ;

BERGOGNE, MC ;

DERUDDER, J ;

DECLERCQ, E ;

IMBACH, JL .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (06) :982-991

← 1 2 3 4 5 →