A RANDOMIZED TRIAL TO EVALUATE THE RISK OF GASTROINTESTINAL-DISEASE DUE TO CONSUMPTION OF DRINKING-WATER MEETING CURRENT MICROBIOLOGICAL STANDARDS

Background: This project directly and empirically measured the level of gastrointestinal (GI) illness related to the consumption of tapwater prepared from sewage-contaminated surface waters and meeting current water quality criteria. Methods: A randomized intervention trial was carried out; 299 eligible households were supplied with domestic water filters (reverse-osmosis) that eliminate microbial and chemical contaminants from their water, and 307 households were left with their usual tapwater without a filter. The GI symptomatology was evaluated by means of a family health diary maintained prospectively by all study families over a 15-month period. Results: The estimated annual incidence of GI illness was 0.76 among tapwater drinkers compared with 0.50 among filtered water drinkers (p < 0.01). These findings were consistently observed in all population subgroups. Conclusion: It is estimated that 35% of the reported GI illnesses among the tapwater drinkers were water-related and preventable. Our results raise questions about the adequacy of current standards of drinking water quality to prevent waterborne endemic gastrointestinal illness.