PREPARATION OF PARTIALLY PROTECTED PEPTIDE THIOESTERS CONTAINING A CYSTEINE RESIDUE AND THEIR SEGMENT CONDENSATION

被引：8

作者：

KWON, Y ^{[1
]}

ZHANG, RH ^{[1
]}

BEMQUERER, MP ^{[1
]}

TOMINAGA, M ^{[1
]}

HOJO, H ^{[1
]}

AIMOTO, S ^{[1
]}

机构：

[1] OSAKA UNIV, INST PROT RES, 3-2 YAMADAOKA, SUITA, OSAKA 565, JAPAN

来源：

CHEMISTRY LETTERS | 1993年 / 05期

关键词：

D O I：

10.1246/cl.1993.881

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Methods for the preparation of partially-protected cysteine-containing peptide segments were developed. The peptide thioester, obtained via a solid-phase method of Boc chemistry, was used for segment condensation with an amino component peptide in the presence of silver ions and N-hydroxysuccinimide to give a desired product in good yield.

引用

页码：881 / 884

页数：4