ETHANOL-PRODUCTION IN A MICROPOROUS HOLLOW-FIBER-BASED EXTRACTIVE FERMENTER WITH IMMOBILIZED YEAST

被引：44

作者：

KANG, WK ^{[1
]}

SHUKLA, R ^{[1
]}

SIRKAR, KK ^{[1
]}

机构：

[1] STEVENS INST TECHNOL LIB,DEPT CHEM & CHEM ENGN,CTR MEMBRANES & SEPARAT TECHNOL,HOBOKEN,NJ 07030

来源：

BIOTECHNOLOGY AND BIOENGINEERING | 1990年 / 36卷 / 08期

关键词：

D O I：

10.1002/bit.260360812

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Microporous‐membrane‐based extractive product recovery in product‐inhibited fermentations allows in situ recovery of inhibitory products in a nondispersive fashion. A tubular bioreactor with continuous strands of hydrophobic microporous hollow fibers having extracting solvent flowing in fiber lumen was utilized for yeast fermentation of glucose to ethanol. Yeast was effectively immobilized on the shell side in small lengths of chopped microporous hyrophilic hollow fibers. The beneficial effects of in situ dispersion‐free solvent ex (oleyl alcohol and dibutyl phthalate) were demonstrated for a 300 g/L glucose substrate feed. Outlet glucose concentration dropped drastically from 123 to 41 g/L as solvent/ substrate flow ratio was increased from 0 to 3 at 9 mL/h of substrate flow rate with oleyl alcohol as extracting solvent. The significant productivity increase with in situ solvent extraction became more evident as solvent/ substrate flow ratio increased. A model of the locally integrated extractive bioreactor describes the observed fermentor performance quite well. Copyright © 1990 John Wiley & Sons, Inc.

引用

页码：826 / 833

页数：8

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