IMMUNOBLOT ANALYSIS OF DYSTROPHIN-RELATED PROTEIN (DRP)

被引：18

作者：

KOGA, R

ISHIURA, S

TAKEMITSU, M

KAMAKURA, K

MATSUZAKI, T

ARAHATA, K

NONAKA, I

SUGITA, H

机构：

[1] NCNP,NATL INST NEUROSCI,KODAIRA,TOKYO 187,JAPAN

[2] UNIV TOKYO,INST APPL MICROBIOL,TOKYO 113,JAPAN

[3] ASAHIKAWA MED COLL,DEPT ORTHOPED SURG,ASAHIKAWA,HOKKAIDO,JAPAN

[4] NATL DEF MED COLL,DEPT INTERNAL MED 3,TOKOROZAWA,SAITAMA 359,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1180卷 / 03期

关键词：

DYSTROPHIN; DYSTROPHIN-RELATED PROTEIN; IMMUNOASSAY;

D O I：

10.1016/0925-4439(93)90047-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Polyclonal antibodies against the carboxy-terminal portion of dystrophin-related protein (DRP), the putative autosomal gene product which shares sequence homology with dystrophin, show the clear expression of DRP in mouse fetal muscle and in cultured human muscle cells, but not in mature mouse or human muscle. DRP has the same molecular mass as X-linked dystrophin and is recovered from the membrane fraction, but is associated with membranes more loosely than dystrophin.

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收藏

页码：257 / 261

页数：5

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