ISOLATION AND STRUCTURAL ELUCIDATION OF PENTACYCLIC TRITERPENOIDS FROM MAPROUNEA-AFRICANA

被引：26

作者：

CHAUDHURI, SK

FULLAS, F

BROWN, DM

WANI, MC

WALL, ME

CAI, LN

MAR, W

LEE, SK

LUO, YD

ZAW, K

FONG, HHS

PEZZUTO, JM

KINGHORN, AD

机构：

[1] RES TRIANGLE INST, CHEM & LIFE SCI GRP, RES TRIANGLE PK, NC 27709 USA

[2] UNIV ILLINOIS, COLL PHARM, DEPT MED CHEM & PHARMACOGNOSY, PROGRAM COLLABORAT RES PHARMACEUT SCI, CHICAGO, IL 60612 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 01期

关键词：

D O I：

10.1021/np50115a001

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Pentacyclic triterpenoids based on the taraxer-14-ene skeleton with a C-28 attached carboxylic acid group have been isolated from the roots of Maprounea africana. These compounds were identified as 1 beta,2 alpha-dihydroxyaleuritolic acid 2,3-bis-p-hydroxybenzoate [1], 2 alpha-hydroxyaleuritolic acid 3-p-hydroxybenzoate [2], 2 alpha-hydroxyaleuritolic acid 2,3-bis-p-hydroxybenzoate [4], aleuritolic acid 3-p-hydroxybenzoate [5], aleuritolic acid [6], and aleuritolic acid 3-acetate [7]. Compounds 1 and 2 are new triterpene esters. Compound 3 was previously reported as 7 beta-hydroxymaprounic acid 3-p-hydroxybenzoate [13]. However, based on detailed nmr studies, its structure has been revised.

引用

页码：1 / 9

页数：9