BETA-HYDROXYSULFOXIMINES IN THE CATALYZED ENANTIOSELECTIVE REDUCTION OF KETONES WITH BORANE

被引：48

作者：

BOLM, C

FELDER, M

机构：

[1] Department of Chemistry, University of Basel, CH-4056 Basel

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 38期

关键词：

ASYMMETRIC REDUCTION; SULFOXIMINES; ENANTIOSELECTIVE CATALYSIS;

D O I：

10.1016/S0040-4039(00)61722-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active beta-hydroxysulfoximines catalyze the asymmetric borane reduction of ketones affording secondary alcohols in high yields with good enantioselectivities (up to 93% ee).

引用

页码：6041 / 6044

页数：4

共 36 条

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[6] X-RAY-DIFFRACTION STUDIES OF CRYSTALLINE TRIHALOMETHYL KETONES (RCOCX3) REVEAL AN UNUSUAL STRUCTURAL DEFORMATION ABOUT THE CARBONYL GROUP
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[7] A MECHANISTIC AND STRUCTURAL-ANALYSIS OF THE BASIS FOR HIGH ENANTIOSELECTIVITY IN THE OXAZABOROLIDINE-CATALYZED REDUCTION OF TRIHALOMETHYL KETONES BY CATECHOLBORANE
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[8] A GENERAL, CATALYTIC, AND ENANTIOSELECTIVE SYNTHESIS OF ALPHA-AMINO-ACIDS
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[9] A NEW PROCESS FOR THE ENANTIOSELECTIVE SYNTHESIS OF CHIRAL ALPHA-ARYLOXY AND ALPHA-HYDROXY ACIDS
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[J]. TETRAHEDRON LETTERS, 1992, 33 (24) : 3431 - 3434
[10] X-RAY CRYSTAL-STRUCTURE OF A CHIRAL OXAZABOROLIDINE CATALYST FOR ENANTIOSELECTIVE CARBONYL REDUCTION
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[J]. TETRAHEDRON LETTERS, 1992, 33 (24) : 3429 - 3430

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