ORGANIZATION OF THE IMMUNE-RESPONSE GENES

被引：142

作者：

UHR, JW

CAPRA, JD

VITETTA, ES

COOK, RG

机构：

来源：

SCIENCE | 1979年 / 206卷 / 4416期

关键词：

D O I：

10.1126/science.113876

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The / region of the major histocompatibility complex contains immune response genes that display considerable polymorphism; that is, there are many alleles at each locus. These genes regulate the immune response to antigen by mediating intercellular communication among lymphoreticular cells. An analysis of the primary structure of the products of two subregions of / (I-A, I-E/C) was undertaken in order to understand the genetic organization of the region, the evolution of the genes and, eventually, their function.

引用

页码：292 / 297

页数：6

共 78 条

[71] THORSBY E, 1974, TRANSPLANT REV-DENMA, V18, P51
[72] IMMUNOLOGICAL DISSECTION OF HUMAN IA MOLECULES
TOSI, R
TANIGAKI, N
CENTIS, D
FERRARA, GB
PRESSMAN, D
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1978, 148 (06) : 1592 - 1611
[73] UNIS EJ, 1971, P NATL ACAD SCI US, V68, P3031
[74] Vitetta E S, 1978, Adv Immunol, V26, P147, DOI 10.1016/S0065-2776(08)60230-8
[75] VITETTA ES, J IMMUNOL
[76] ORIENTATION OF CELL-SURFACE ANTIGENS IN LIPID BILAYER OF LYMPHOCYTE PLASMA-MEMBRANE
WALSH, FS
CRUMPTON, MJ
[J]. NATURE, 1977, 269 (5626) : 307 - 311
[77] WERNET P, 1975, TRANSPL P S1, V7, P193
[78] WINCHESTER RJ, 1975, HISTOCOMPATIBILITY T

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