CONVERSION OF AVERMECTIN-B1 TO 19-EPI-AVERMECTIN-B1

被引：10

作者：

BLIZZARD, T

BOSTROM, L

MARGIATTO, G

MROZIK, H

FISHER, M

机构：

[1] Merck Sharp Dohme Research Laboratories R50G-231, Rahway, NJ 07065

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 24期

关键词：

D O I：

10.1016/0040-4039(91)85068-G

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Avermectin B1 (1) has been converted to 19-epi-avermectin B1 (2) in six steps. Analog 2 retains some bioactivity but is substantially less bioactive than 1.

引用

页码：2723 / 2726

页数：4

共 19 条

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