ATROPO-ENANTIOSELECTIVE BIARYL SYNTHESIS BY STEREOCONTROLLED CLEAVAGE OF CONFIGURATIVELY LABILE LACTONE-BRIDGED PRECURSORS USING CHIRAL H-NUCLEOPHILES

被引：70

作者：

BRINGMANN, G

HARTUNG, T

机构：

[1] Institute of Organic Chemistry, University of Würzburg, D-97074 Würzburg, Am Hubland

来源：

TETRAHEDRON | 1993年 / 49卷 / 36期

关键词：

D O I：

10.1016/S0040-4020(01)88014-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The atropo-enantioselective synthesis of axially stereogenic, sterically shielded biaryl systems is described, by stereocontrolled ring opening of the corresponding lactone-bridged, still configurationally labile precursors. The atropenantiomer excesses range up to 97% ee.

引用

页码：7891 / 7902

页数：12

共 32 条

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BRINGMANN, G
HARTUNG, T
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