BIOACTIVE NORSESTERTERPENE 1,2-DIOXANES FROM A THAI SPONGE, MYCALE SP

被引：53

作者：

TANAKA, J

HIGA, T

SUWANBORIRUX, K

KOKPOL, U

BERNARDINELLI, G

JEFFORD, CW

机构：

[1] UNIV RYUKYUS,DEPT MARINE SCI,NISHIHARA,OKINAWA 90301,JAPAN

[2] CHULALONGKORN UNIV,DEPT PHARMACOGNOSY,BANGKOK 10500,THAILAND

[3] UNIV GENEVA,CRYSTALLOG LAB,CH-1211 GENEVA 4,SWITZERLAND

[4] UNIV GENEVA,DEPT ORGAN CHEM,CH-1211 GENEVA 4,SWITZERLAND

[5] CHULALONGKORN UNIV,DEPT CHEM,BANGKOK 10500,THAILAND

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 11期

关键词：

D O I：

10.1021/jo00063a016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new norsesterterpene 1,2-dioxanes, mycaperoxides A (2) and B (3), have been isolated from a Thai sponge of the genus Mycale. Their relative structures were determined by X-ray and spectroscopic methods and their absolute configurations assigned by applying the Kusumi and Kakisawa modification of Mosher's method. Both compounds showed significant cytotoxicity and in vitro antiviral activity.

引用

页码：2999 / 3002

页数：4

共 14 条

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