Telomeres - what's new at the end ?

被引：18

作者：

Henderson, Eric R. ^{[1
]}

Larson, Drena D. ^{[1
]}

机构：

[1] Iowa State Univ, Dept Zool & Genet, Ames, IA 50011 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1991年 / 1卷 / 04期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1016/S0959-437X(05)80205-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Telomeres are specialized chromatin domains located at the ends of chromosomes. They are involved in chromosome replication, stability and localization in the nucleus. In addition to these functions, recent work suggests that telomeres are involved in such superficially diverse cellular phenomena as ageing, cancer, nuclear architecture and nuclear/cellular division.

引用

页码：538 / 543

页数：6

共 72 条

[31] TEMPORAL AND SPATIAL COORDINATION OF CHROMOSOME MOVEMENT, SPINDLE FORMATION, AND NUCLEAR-ENVELOPE BREAKDOWN DURING PROMETAPHASE IN DROSOPHILA-MELANOGASTER EMBRYOS [J].

HIRAOKA, Y ;

AGARD, DA ;

SEDAT, JW .

JOURNAL OF CELL BIOLOGY, 1990, 111 (06) :2815-2828

[32] RAP-1 FACTOR IS NECESSARY FOR DNA LOOP FORMATION INVITRO AT THE SILENT MATING TYPE LOCUS HML [J].

HOFMANN, JFX ;

LAROCHE, T ;

BRAND, AH ;

GASSER, SM .

CELL, 1989, 57 (05) :725-737

[33]

JAMES TC, 1989, EUR J CELL BIOL, V50, P170

[34] DYNAMICS OF TELOMERE LENGTH VARIATION IN TETRAHYMENA THERMOPHILA [J].

LARSON, DD ;

SPANGLER, EA ;

BLACKBURN, EH .

CELL, 1987, 50 (03) :477-483

[35]

LEVIS R, 1985, DROSOPHILA, V229, P558

[36] VIABLE DELETIONS OF A TELOMERE FROM A DROSOPHILA CHROMOSOME [J].

LEVIS, RW .

CELL, 1989, 58 (04) :791-801

[37] A YEAST PROTEIN THAT BINDS TO VERTEBRATE TELOMERES AND CONSERVED YEAST TELOMERIC JUNCTIONS [J].

LIU, ZP ;

TYE, BK .

GENES & DEVELOPMENT, 1991, 5 (01) :49-59

[38] A YEAST TELOMERE BINDING-ACTIVITY BINDS TO 2 RELATED TELOMERE SEQUENCE MOTIFS AND IS INDISTINGUISHABLE FROM RAP1 [J].

LONGTINE, MS ;

WILSON, NM ;

PETRACEK, ME ;

BERMAN, J .

CURRENT GENETICS, 1989, 16 (04) :225-239

[39] A MUTANT WITH A DEFECT IN TELOMERE ELONGATION LEADS TO SENESCENCE IN YEAST [J].

LUNDBLAD, V ;

SZOSTAK, JW .

CELL, 1989, 57 (04) :633-643

[40]

LUNDBLAD V, 1990, CELL, V60, P529

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