PEPTIDE SELECTION BY CLASS-I MOLECULES OF THE MAJOR HISTOCOMPATIBILITY COMPLEX

被引：80

作者：

ELLIOTT, T ^{[1
]}

SMITH, M ^{[1
]}

DRISCOLL, P ^{[1
]}

MCMICHAEL, A ^{[1
]}

机构：

[1] UNIV OXFORD, DEPT BIOCHEM, OXFORD, ENGLAND

来源：

CURRENT BIOLOGY | 1993年 / 3卷 / 12期

关键词：

D O I：

10.1016/0960-9822(93)90219-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Class I molecules of the major histocompatibility complex (MHC) bind peptides derived from cytoplasmic proteins. Comparison of over 100 such peptides reveals the importance of the carboxy-terminal residue in selective binding. Recent evidence implicates the proteases and transporters of the processing pathway in providing peptides with the correct residues at the carboxyl terminus. © 1993.

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页码：854 / 866

页数：13

相关论文

共 101 条

[1]

Alberts B, 2017, MOL BIOL CELL

[2] ENDOGENOUSLY SYNTHESIZED PEPTIDE WITH AN ENDOPLASMIC-RETICULUM SIGNAL SEQUENCE SENSITIZES ANTIGEN PROCESSING MUTANT-CELLS TO CLASS-I-RESTRICTED CELL-MEDIATED LYSIS [J].

ANDERSON, K ;

CRESSWELL, P ;

GAMMON, M ;

HERMES, J ;

WILLIAMSON, A ;

ZWEERINK, H .

JOURNAL OF EXPERIMENTAL MEDICINE, 1991, 174 (02) :489-492

[3] EVIDENCE THAT TRANSPORTERS ASSOCIATED WITH ANTIGEN-PROCESSING TRANSLOCATE A MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I-BINDING PEPTIDE INTO THE ENDOPLASMIC-RETICULUM IN AN ATP-DEPENDENT MANNER [J].

ANDROLEWICZ, MJ ;

ANDERSON, KS ;

CRESSWELL, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (19) :9130-9134

[4] PROTEASOME SUBUNITS ENCODED IN THE MHC ARE NOT GENERALLY REQUIRED FOR THE PROCESSING OF PEPTIDES BOUND BY MHC CLASS-I MOLECULES [J].

ARNOLD, D ;

DRISCOLL, J ;

ANDROLEWICZ, M ;

HUGHES, E ;

CRESSWELL, P ;

SPIES, T .

NATURE, 1992, 360 (6400) :171-174

[5]

BANGHAM CRM, 1989, T CELLS, P281

[6] DEFINITION OF A MINIMAL OPTIMAL CYTOTOXIC T-CELL EPITOPE WITHIN THE HEPATITIS-B VIRUS NUCLEOCAPSID PROTEIN [J].

BERTOLETTI, A ;

CHISARI, FV ;

PENNA, A ;

GUILHOT, S ;

GALATI, L ;

MISSALE, G ;

FOWLER, P ;

SCHLICHT, HJ ;

VITIELLO, A ;

CHESNUT, RC ;

FIACCADORI, F ;

FERRARI, C .

JOURNAL OF VIROLOGY, 1993, 67 (04) :2376-2380

[7] STRUCTURE OF THE HUMAN CLASS-I HISTOCOMPATIBILITY ANTIGEN, HLA-A2 [J].

BJORKMAN, PJ ;

SAPER, MA ;

SAMRAOUI, B ;

BENNETT, WS ;

STROMINGER, JL ;

WILEY, DC .

NATURE, 1987, 329 (6139) :506-512

[8] THE FOREIGN ANTIGEN-BINDING SITE AND T-CELL RECOGNITION REGIONS OF CLASS-I HISTOCOMPATIBILITY ANTIGENS [J].

BJORKMAN, PJ ;

SAPER, MA ;

SAMRAOUI, B ;

BENNETT, WS ;

STROMINGER, JL ;

WILEY, DC .

NATURE, 1987, 329 (6139) :512-518

[9] PEPTIDE-INDUCED CONFORMATIONAL-CHANGES IN CLASS-I HEAVY-CHAINS ALTER MAJOR HISTOCOMPATIBILITY COMPLEX RECOGNITION [J].

BLUESTONE, JA ;

JAMESON, S ;

MILLER, S ;

DICK, R .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 176 (06) :1757-1761

[10] ENHANCED RECOGNITION OF A MODIFIED PEPTIDE ANTIGEN BY CYTOTOXIC-T CELLS SPECIFIC FOR INFLUENZA NUCLEOPROTEIN [J].

BODMER, HC ;

PEMBERTON, RM ;

ROTHBARD, JB ;

ASKONAS, BA .

CELL, 1988, 52 (02) :253-258

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