SOMATOSTATIN RECEPTOR SCINTIGRAPHY AND ENDOSCOPIC ULTRASONOGRAPHY IN THE DIAGNOSIS OF INSULINOMA AND GASTRINOMA

被引：14

作者：

ZIMMER, T ^{[1
]}

STOLZEL, U ^{[1
]}

LIEHR, RM ^{[1
]}

BADER, M ^{[1
]}

FETT, U ^{[1
]}

HAMM, B ^{[1
]}

WIEDENMANN, B ^{[1
]}

RIECKEN, EO ^{[1
]}

机构：

[1] UNIV KLINIKUM BENJAMIN FRANKLIN, RADIOL KLIN & POLIKLIN, RADIOL DIAGNOST & NUKL MED ABT, D-12200 BERLIN, GERMANY

来源：

DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT | 1995年 / 120卷 / 04期

关键词：

D O I：

10.1055/s-2008-1047641

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In a prospective study of 13 patients (three males and 10 females; mean age 53 [8-82] years) the value of somatostatin receptor scintigraphy (SRS) and endoscopic ultrasonography (EUS) was compared with transabdominal ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) in the diagnosis of insulinoma (six patients) or gastrinoma (seven patients). There were ten separate primary lesions of each tumour type, proven histologically. For insulinoma the sensitivity of EUS was 90%, SRS 10% and CT, US and MRI together 20%. For gastrinoma the sensitivity of EUS was 90%, SRS 100%, and 30% for the other three methods together. Thus EUS had a high diagnostic localizing sensitivity for both tumors, while SRS was highly sensitive only in the diagnosis of gastrinoma, not insulinoma. The value of CT, MRI and conventional ultrasonography lies in their ability to visualize distant metastases.

引用

页码：87 / 93

页数：7

共 36 条

[11]

JOHN M, 1993, Z GASTROENTEROL S, V31, P510

[12] RECEPTOR SCINTIGRAPHY IN HORMONE-PRODUCING GASTROINTESTINAL AND PANCREATIC TUMORS [J].

JOSEPH, K ;

STAPP, J ;

REINECKE, J ;

HOFFKEN, H ;

BENNING, R ;

NEUHAUS, C ;

TRAUTMANN, ME ;

SCHWERK, WB ;

ARNOLD, R .

DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 1992, 117 (26) :1025-1028

[13]

KRENNING EP, 1989, LANCET, V1, P242

[14] IN-111 OCTREOTIDE SCINTIGRAPHY IN ONCOLOGY [J].

KRENNING, EP ;

KWEKKEBOOM, DJ ;

REUBI, JC ;

VANHAGEN, PM ;

VANEIJCK, CHJ ;

OEI, HY ;

LAMBERTS, SWJ .

METABOLISM-CLINICAL AND EXPERIMENTAL, 1992, 41 (09) :83-86

[15]

KRENNING EP, 1994, IN PRESS ANN NY ACAD

[16] LOCALIZATION OF ISLET CELL TUMORS BY DYNAMIC CT - COMPARISON WITH PLAIN CT, ARTERIOGRAPHY, SONOGRAPHY, AND VENOUS SAMPLING [J].

KRUDY, AG ;

DOPPMAN, JL ;

JENSEN, RT ;

NORTON, JA ;

COLLEN, MJ ;

SHAWKER, TH ;

GARDNER, JD ;

MCARTHUR, K ;

GORDEN, P .

AMERICAN JOURNAL OF ROENTGENOLOGY, 1984, 143 (03) :585-589

[17] PARALLEL INVIVO AND INVITRO DETECTION OF FUNCTIONAL SOMATOSTATIN RECEPTORS IN HUMAN ENDOCRINE PANCREATIC TUMORS - CONSEQUENCES WITH REGARD TO DIAGNOSIS, LOCALIZATION, AND THERAPY [J].

LAMBERTS, SWJ ;

HOFLAND, LJ ;

VANKOETSVELD, PM ;

REUBI, JC ;

BRUINING, HA ;

BAKKER, WH ;

KRENNING, EP .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1990, 71 (03) :566-574

[18] SOMATOSTATIN-RECEPTOR IMAGING IN THE LOCALIZATION OF ENDOCRINE TUMORS [J].

LAMBERTS, SWJ ;

BAKKER, WH ;

REUBI, JC ;

KRENNING, EP .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (18) :1246-1249

[19]

LENZE H, 1993, GASTROENTEROLOGY, V104, pA316

[20]

LIGHTDALE CJ, 1991, CANCER, V68, P1815, DOI 10.1002/1097-0142(19911015)68:8<1815::AID-CNCR2820680828>3.0.CO

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