FREQUENCY OF ISONIAZID ACETYLASE ENZYME DEFICIENCY AMONG EGYPTIANS

被引:25
作者
HASHEM, N
KHALIFA, S
NOUR, A
机构
[1] Medical Genetics Unit, Ain-Shams University, Cairo
关键词
D O I
10.1002/ajpa.1330310114
中图分类号
Q98 [人类学];
学科分类号
030303 ;
摘要
The frequency of isoniazid slow inactivators is very high among Eqyptians, 82% have more than 0.91 γ/ml of free INH in serum specimens obtained six hours after a single dose of 10 mgm/kgm. The incidence of the allele for INH acetylase enzyme deficiency is estimated at 0.9059 and that of the heterozygous carrier of this allele at 0.1705. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company
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页码:97 / &
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[11]  
SUNAHARA S, 1961, KEKKAKU, V36, P521