GRAFT VS LEUKEMIA REACTIONS IN CHRONIC MYELOID-LEUKEMIA

被引：5

作者：

CULLIS, JO ^{[1
]}

BARRETT, AJ ^{[1
]}

GOLDMAN, JM ^{[1
]}

机构：

[1] ROYAL POSTGRAD MED SCH,DEPT HAEMATOL,MRC,LRF,LEUKAEMIA UNIT,DU CANE RD,LONDON W12 0HS,ENGLAND

来源：

EUROPEAN JOURNAL OF CANCER | 1992年 / 28A卷 / 12期

关键词：

D O I：

10.1016/0959-8049(92)90257-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 39-year-old female relapsed 36 months after allogeneic bone marrow transplantation for chronic myeloid leukaemia. Infusion of peripheral blood leucocytes from her bone marrow donor resulted in complete remission, and she remains leukaemia-free 18 months later. This case provides direct evidence for a 'graft vs. leukaemia' (GVL) effect contributing to the eradication of leukaemia after marrow transplantation. Existing evidence for GVL and its possible mechanisms are reviewed.

引用

页码：2069 / 2074

页数：6

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