INTRONS AND EXONS

被引：74

作者：

PATTHY, L

机构：

[1] Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, Budapest

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(94)90108-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Analysis of the exon-intron structures of genes, and a survey of the evolutionary distribution of mosaic proteins suggest that modularization of protein domains by intron insertions and their dispersal through exon-shuffling become significant on ly in higher eukaryotes. The appearance of this powerful evolutionary mechanism probably contributed significantly to the 'Big Bang' of metazoan radiation.

引用

收藏

页码：383 / 392

页数：10

相关论文

共 79 条

[1] TESTICAN, A MULTIDOMAIN TESTICULAR PROTEOGLYCAN RESEMBLING MODULATORS OF CELL SOCIAL-BEHAVIOR [J].

ALLIEL, PM ;

PERIN, JP ;

JOLLES, P ;

BONNET, FJ .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1993, 214 (01) :347-350

[2] DROSOPHILA HAS A TWITCHIN TITIN-RELATED GENE THAT APPEARS TO ENCODE PROJECTIN [J].

AYMESOUTHGATE, A ;

VIGOREAUX, J ;

BENIAN, G ;

PARDUE, ML .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (18) :7973-7977

[3] A RECEPTOR FOR SUBGROUP-A ROUS-SARCOMA VIRUS IS RELATED TO THE LOW-DENSITY-LIPOPROTEIN RECEPTOR [J].

BATES, P ;

YOUNG, JAT ;

VARMUS, HE .

CELL, 1993, 74 (06) :1043-1051

[4] AN ADHESIVE DOMAIN DETECTED IN FUNCTIONALLY DIVERSE RECEPTORS [J].

BECKMANN, G ;

BORK, P .

TRENDS IN BIOCHEMICAL SCIENCES, 1993, 18 (02) :40-41

[5] AN EXPANDING UNIVERSE OF INTRONS [J].

BELFORT, M .

SCIENCE, 1993, 262 (5136) :1009-1010

[6]

BORK P, 1993, PROTEIN SCI, V2, P669

[7] THE CUB DOMAIN - A WIDESPREAD MODULE IN DEVELOPMENTALLY-REGULATED PROTEINS [J].

BORK, P ;

BECKMANN, G .

JOURNAL OF MOLECULAR BIOLOGY, 1993, 231 (02) :539-545

[8] STRUCTURE OF THE DROSOPHILA GENE FOR THE LAMININ-B2 CHAIN [J].

CHI, HC ;

JUMINAGA, D ;

WANG, SY ;

HUI, CF .

DNA AND CELL BIOLOGY, 1991, 10 (06) :451-466

[9] STRUCTURAL CHARACTERIZATION OF THE COMPLETE HUMAN PERLECAN GENE AND ITS PROMOTER [J].

COHEN, IR ;

GRASSEL, S ;

MURDOCH, AD ;

IOZZO, RV .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (21) :10404-10408

[10]

COLLINS T, 1991, J BIOL CHEM, V266, P2466

← 1 2 3 4 5 6 7 8 →