INTRONS AND EXONS

被引：74

作者：

PATTHY, L

机构：

[1] Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, Budapest

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(94)90108-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Analysis of the exon-intron structures of genes, and a survey of the evolutionary distribution of mosaic proteins suggest that modularization of protein domains by intron insertions and their dispersal through exon-shuffling become significant on ly in higher eukaryotes. The appearance of this powerful evolutionary mechanism probably contributed significantly to the 'Big Bang' of metazoan radiation.

引用

页码：383 / 392

页数：10

共 79 条

[51] A FAMILY OF LAMININ-RELATED PROTEINS CONTROLLING ECTODERMAL DIFFERENTIATION IN DROSOPHILA [J].