PLASMID-BASED TRANSGENIC MOUSE MODEL FOR STUDYING IN-VIVO MUTATIONS

被引:123
作者
BOERRIGTER, METI [1 ]
DOLLE, MET [1 ]
MARTUS, HJ [1 ]
GOSSEN, JA [1 ]
VIJG, J [1 ]
机构
[1] HARVARD UNIV,SCH MED,BOSTON,MA 02215
关键词
D O I
10.1038/377657a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 [理学]; 0710 [生物学]; 09 [农学];
摘要
A new transgenic mouse model for studying in vivo somatic mutations is based on the efficient recovery of chromosomally integrated lacZ-containing plasmids, using magnetic beads.
引用
收藏
页码:657 / 659
页数:3
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