IGE - AN IMMUNOGLOBULIN SPECIALIZED IN ANTIGEN CAPTURE

被引：61

作者：

MUDDE, GC ^{[1
]}

HANSEL, TT ^{[1
]}

VONREIJSEN, FC ^{[1
]}

OSTERHOFF, BF ^{[1
]}

BRUIJNZEELKOOMEN, CAFM ^{[1
]}

机构：

[1] SWISS INST ALLERGY & ASTHMA RES,DEPT ASTHMA,DAVOS,SWITZERLAND

来源：

IMMUNOLOGY TODAY | 1990年 / 11卷 / 12期

关键词：

D O I：

10.1016/0167-5699(90)90172-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

IgE bound to the low-affinity receptor for immunoglobulin E (FC-epsilon-R) on antigen-presenting cells (APCs) may permit binding of antigens to APCs prior to their processing and presentation. Here, G.C. Mudde and colleagues argue that the unique characteristics of IgE serological responses together with the distribution of FC-epsilon-RII (CD23) ON APCs are consistent with this novel function of IgE. The concept of IgE involvement in antigen capture is discussed in relation to Langerhans cells, B cells and follicular dendritic cells.

引用

页码：440 / 443

页数：4

共 50 条

[1] INDUCTION OF FC-EPSILON-R2/CD23 ON HUMAN EPIDERMAL LANGERHANS CELLS BY HUMAN RECOMBINANT INTERLEUKIN-4 AND GAMMA-INTERFERON [J].

BIEBER, T ;

RIEGER, A ;

NEUCHRIST, C ;

PRINZ, JC ;

RIEBER, EP ;

BOLTZNITULESCU, G ;

SCHEINER, O ;

KRAFT, D ;

RING, J ;

STINGL, G .

JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 170 (01) :309-314

[2]

BLASER K, 1989, ALLERGOLOGIE, V12, pS44

[3] THE LOW-AFFINITY RECEPTOR FOR IGE (CD23) ON LYMPHOCYTES-B IS SPATIALLY ASSOCIATED WITH HLA-DR ANTIGENS [J].

BONNEFOY, JY ;

GUILLOT, O ;

SPITS, H ;

BLANCHARD, D ;

ISHIZAKA, K ;

BANCHEREAU, J .

JOURNAL OF EXPERIMENTAL MEDICINE, 1988, 167 (01) :57-72

[4]

BRUIJNZEELKOOM CAF, 1988, CLIN EXP IMMUNOL, V74, P137

[5]

BRUIJNZEELKOOME.C, 1986, ARCH DERMATOL RES, V278, P199

[6]

CAPRON M, 1987, J IMMUNOL, V139, P2059

[7]

CASTEN LA, 1988, J IMMUNOL, V140, P404

[8]

CHAN MA, 1990, J IMMUNOL, V144, P3563

[9] QUANTITATIVE ASSESSMENTS OF IGG AND IGE ANTIBODIES TO INHALANT ALLERGENS IN PATIENTS WITH ATOPIC-DERMATITIS [J].

CHAPMAN, MD ;

ROWNTREE, S ;

MITCHELL, EB ;

DEFUENMAJOR, MCD ;

PLATTSMILLS, TAE .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1983, 72 (01) :27-33

[10]

CHESNUT RW, 1981, J IMMUNOL, V126, P1075

← 1 2 3 4 5 →