IGE - AN IMMUNOGLOBULIN SPECIALIZED IN ANTIGEN CAPTURE

被引：61

作者：

MUDDE, GC ^{[1
]}

HANSEL, TT ^{[1
]}

VONREIJSEN, FC ^{[1
]}

OSTERHOFF, BF ^{[1
]}

BRUIJNZEELKOOMEN, CAFM ^{[1
]}

机构：

[1] SWISS INST ALLERGY & ASTHMA RES,DEPT ASTHMA,DAVOS,SWITZERLAND

来源：

IMMUNOLOGY TODAY | 1990年 / 11卷 / 12期

关键词：

D O I：

10.1016/0167-5699(90)90172-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

IgE bound to the low-affinity receptor for immunoglobulin E (FC-epsilon-R) on antigen-presenting cells (APCs) may permit binding of antigens to APCs prior to their processing and presentation. Here, G.C. Mudde and colleagues argue that the unique characteristics of IgE serological responses together with the distribution of FC-epsilon-RII (CD23) ON APCs are consistent with this novel function of IgE. The concept of IgE involvement in antigen capture is discussed in relation to Langerhans cells, B cells and follicular dendritic cells.

引用

页码：440 / 443

页数：4

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