COMPARISON OF THE PHARMACOLOGY OF NAFARELIN AND DANAZOL

被引:10
作者
BARBIERI, RL
机构
[1] Department of Obstetrics and Gynecology, Harvard Medical School, Brigham and Women's Hospital Boston, MA
关键词
Danazol; endometriosis; gonadotropin-releasing hormone agonists; nafarelin;
D O I
10.1016/0002-9378(90)90436-B
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The pharmacologic profiles of danazol and nafarelin differ considerably from each other. Danazol interacts with multiple classes of proteins, whereas the gonadotropin-releasing hormone agonist nafarelin interacts only with the pituitary gonadotropin-releasing hormone receptor. Differences in the molecular, endocrine, and clinical pharmacologic properties of these agents may provide clues to their varying effects in the management of women with endometriosis. © 1990.
引用
收藏
页码:581 / 585
页数:5
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