COMPARISON OF THE PHARMACOLOGY OF NAFARELIN AND DANAZOL

被引：10

作者：

BARBIERI, RL

机构：

[1] Department of Obstetrics and Gynecology, Harvard Medical School, Brigham and Women's Hospital Boston, MA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1990年 / 162卷 / 02期

关键词：

Danazol; endometriosis; gonadotropin-releasing hormone agonists; nafarelin;

D O I：

10.1016/0002-9378(90)90436-B

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The pharmacologic profiles of danazol and nafarelin differ considerably from each other. Danazol interacts with multiple classes of proteins, whereas the gonadotropin-releasing hormone agonist nafarelin interacts only with the pituitary gonadotropin-releasing hormone receptor. Differences in the molecular, endocrine, and clinical pharmacologic properties of these agents may provide clues to their varying effects in the management of women with endometriosis. © 1990.

引用

页码：581 / 585

页数：5

共 18 条

[11]

HILL JA, 1987, FERTIL STERIL, V47, P114

[12] THE INTERACTION OF HUMAN ENDOMETRIAL AND MYOMETRIAL STEROID-RECEPTORS WITH DANAZOL [J].