STUDIES OF ISONIAZID METABOLISM IN ISOLATED RAT HEPATOCYTES BY MASS FRAGMENTOGRAPHY

被引：20

作者：

NODA, A ^{[1
]}

HSU, KY ^{[1
]}

ASO, Y ^{[1
]}

MATSUYAMA, K ^{[1
]}

IGUCHI, S ^{[1
]}

HIRATA, M ^{[1
]}

机构：

[1] SHIONOGI & CO LTD,SHIONOGI RES LAB,OSAKA 553,JAPAN

来源：

JOURNAL OF CHROMATOGRAPHY | 1982年 / 230卷 / 02期

关键词：

D O I：

10.1016/S0378-4347(00)80484-3

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

引用

页码：345 / 352

页数：8

共 8 条

[1]

GOROMARU T, 1977, YAKUZAIGAKU, V37, P23

[2] METABOLISM OF ISONIAZID AND FREE HYDRAZINE FORMATION IN ISOLATED RAT HEPATOCYTES [J].

HIRATA, M ;

ASO, Y ;

HSU, KY ;

TABATA, T ;

NODA, A ;

IGUCHI, S .

JOURNAL OF PHARMACOBIO-DYNAMICS, 1981, 4 (02) :145-147

[3]

HORBERG J, 1977, EUR J BIOCH, V74, P77

[4]

IGUCHI S, 1977, CHEM PHARM BULL, V25, P2796

[5]

KANEO Y, 1981, J PHARMACOBIO-DYNAM, V4, pS24

[6]

Moldeus P, 1978, Methods Enzymol, V52, P60

[7] ISONIAZID AND IPRONIAZID - ACTIVATION OF METABOLITES TO TOXIC INTERMEDIATES IN MAN AND RAT [J].

NELSON, SD ;

MITCHELL, JR ;

TIMBRELL, JA ;

SNODGRASS, WR ;

CORCORAN, GB .

SCIENCE, 1976, 193 (4256) :901-903

[8]

NODA A, 1978, Journal of Pharmacobio-Dynamics, V1, P132

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