STRUCTURAL CONSENSUS OF RNA TEMPLATES REPLICATED BY Q-BETA REPLICASE

被引：11

作者：

VORONIN, LA

机构：

[1] Institute of Protein Research, Russian Academy of Sciences, 142292 Pushchino, Moscow Region

来源：

BIOCHIMIE | 1992年 / 74卷 / 05期

关键词：

Q-BETA PHAGE REPLICASE; REPLICATING RNA; STRUCTURAL CONSENSUS;

D O I：

10.1016/0300-9084(92)90090-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Q-beta-replicase replicates a variety of enzyme-specific small RNAs in addition to the phage genomic RNA. The sequence analysis has revealed that all these RNAs are potentially capable of forming a consensus secondary structure element. It represents a stalk which is formed by the 5'-GGG... and ...CCCA-3' complementary stretches at the termini of the replicating RNA molecules and adjacent 5'- and 3'-hairpins, which may form a stacking with the stalk. The structure found is rather similar to the analogous structure in the tRNA molecule. The genomic RNA of the Q-beta-phage and other related phages can also form a similar structural element.

引用

收藏

页码：491 / 494

页数：4

相关论文

共 15 条

[1] COMPLETE NUCLEOTIDE-SEQUENCE OF THE GROUP-I RNA BACTERIOPHAGE FR [J].

ADHIN, MR ;

AVOTS, A ;

BERZIN, V ;

OVERBEEK, GP ;

VANDUIN, J .

BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1050 (1-3) :104-109

[2] SECONDARY STRUCTURE AT THE 3' TERMINAL REGION OF RNA COLIPHAGES - COMPARISON WITH TRANSFER-RNA [J].

ADHIN, MR ;

ALBLAS, J ;

VANDUIN, J .

BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1050 (1-3) :110-118

[3] REPLICATION AND EVOLUTION OF SHORT-CHAINED RNA SPECIES REPLICATED BY Q-BETA REPLICASE [J].

BIEBRICHER, CK .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1987, 52 :299-306

[4] COMPLETE NUCLEOTIDE-SEQUENCE OF BACTERIOPHAGE MS2-RNA - PRIMARY AND SECONDARY STRUCTURE OF REPLICASE GENE [J].

FIERS, W ;

CONTRERAS, R ;

DUERINCK, F ;

HAEGEMAN, G ;

ISERENTANT, D ;

MERREGAERT, J ;

MINJOU, W ;

MOLEMANS, F ;

RAEYMAEKERS, A ;

VANDENBERGHE, A ;

VOLCKAERT, G ;

YSEBAERT, M .

NATURE, 1976, 260 (5551) :500-507

[5] RECOGNITION OF SIZE AND SEQUENCE BY AN RNA REPLICASE [J].

HARUNA, I ;

SPIEGELMAN, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1965, 54 (04) :1189-+

[6] SPECIFIC TEMPLATE REQUIREMENTS OF RNA REPLICASES [J].

HARUNA, I ;

SPIEGELM.S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1965, 54 (02) :579-&

[7] ANALYSIS OF THE COMPLETE NUCLEOTIDE-SEQUENCE OF THE GROUP IV RNA COLIPHAGE SP [J].

INOKUCHI, Y ;

JACOBSON, AB ;

HIROSE, T ;

INAYAMA, S ;

HIRASHIMA, A .

NUCLEIC ACIDS RESEARCH, 1988, 16 (13) :6205-6221

[8] REPLICATING RNA MOLECULE SUITABLE FOR A DETAILED ANALYSIS OF EXTRACELLULAR EVOLUTION AND REPLICATION [J].

KACIAN, DL ;

SPIEGELMAN, S ;

MILLS, DR ;

KRAMER, FR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (10) :3038-+

[9]

MEKLER P, 1981, THESIS U ZURICH

[10] AN INVIVO RECOMBINANT RNA CAPABLE OF AUTOCATALYTIC SYNTHESIS BY Q-BETA-REPLICASE [J].

MUNISHKIN, AV ;

VORONIN, LA ;

CHETVERIN, AB .

NATURE, 1988, 333 (6172) :473-475