PRENATAL ONTOGENY OF D2 DOPAMINE-RECEPTOR AND DOPAMINE TRANSPORTER GENE-EXPRESSION IN THE RAT MESENCEPHALON

被引：16

作者：

TISON, F

NORMAND, E

BLOCH, B

机构：

[1] URA-CNRS 1200, Laboratoire d'Histologie et Embryologie (UFR II), Université de Bordeaux II, 33076 Bordeaux Cédex

来源：

NEUROSCIENCE LETTERS | 1994年 / 166卷 / 01期

关键词：

D2 DOPAMINE RECEPTOR; DOPAMINE TRANSPORTER; ONTOGENY; MESENCEPHALON; IN SITU HYBRIDIZATION;

D O I：

10.1016/0304-3940(94)90837-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This work demonstrates the early prenatal expression (by gestational day 14) of dopamine D2 receptor and dopamine transporter mRNAs by immature dopaminergic cells of the rat mesencephalon using in situ hybridization. Our results indicate that mRNAs are detectable 3 days before the appearance of functional D2 presynaptic receptors and detectable dopamine release at striatal terminals.

引用

页码：48 / 50

页数：3

共 16 条

[1] CLONING AND EXPRESSION OF A RAT D2 DOPAMINE RECEPTOR CDNA [J].

BUNZOW, JR ;

VANTOL, HHM ;

GRANDY, DK ;

ALBERT, P ;

SALON, J ;

CHRISTIE, MJ ;

MACHIDA, CA ;

NEVE, KA ;

CIVELLI, O .

NATURE, 1988, 336 (6201) :783-787

[2] ONTOGENY OF TYROSINE-HYDROXYLASE AND CHOLECYSTOKININ GENE-EXPRESSION IN THE RAT MESENCEPHALON [J].

BURGUNDER, JM ;

YOUNG, WS .

DEVELOPMENTAL BRAIN RESEARCH, 1990, 52 (1-2) :85-93

[3] PRENATAL D1, D1B AND D3 DOPAMINE-RECEPTOR GENE-EXPRESSION IN THE RAT FOREBRAIN - DETECTION BY REVERSE POLYMERASE CHAIN-REACTION [J].

CADORET, MA ;

JABER, M ;

BLOCH, B .

NEUROSCIENCE LETTERS, 1993, 155 (01) :92-95

[4] DIFFERENTIAL ONTOGENY OF FUNCTIONAL DOPAMINE AND MUSCARINIC RECEPTORS MEDIATING PRESYNAPTIC INHIBITION OF NEUROTRANSMITTER RELEASE AND POSTSYNAPTIC REGULATION OF ADENYLATE-CYCLASE ACTIVITY IN RAT STRIATUM [J].

DEVRIES, TJ ;

MULDER, AH ;

SCHOFFELMEER, ANM .

DEVELOPMENTAL BRAIN RESEARCH, 1992, 66 (01) :91-96

[5] ONTOGENY OF DOPAMINE TRANSPORTER MESSENGER-RNA EXPRESSION IN THE RAT-BRAIN [J].

FUJITA, M ;

SHIMADA, S ;

NISHIMURA, T ;

UHL, GR ;

TOHYAMA, M .

MOLECULAR BRAIN RESEARCH, 1993, 19 (03) :222-226

[6] COMPLETE CODING SEQUENCE OF RAT TYROSINE-HYDROXYLASE MESSENGER-RNA [J].

GRIMA, B ;

LAMOUROUX, A ;

BLANOT, F ;

BIGUET, NF ;

MALLET, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (02) :617-621

[7] D2 DOPAMINE RECEPTOR GENE-EXPRESSION IN THE RAT STRIATUM DURING ONTOGENY - AN INSITU HYBRIDIZATION STUDY [J].

GUENNOUN, R ;

BLOCH, B .

DEVELOPMENTAL BRAIN RESEARCH, 1991, 60 (01) :79-87

[8] ONTOGENY OF D1 AND DARPP-32 GENE-EXPRESSION IN THE RAT STRIATUM - AN INSITU HYBRIDIZATION STUDY [J].

GUENNOUN, R ;

BLOCH, B .

MOLECULAR BRAIN RESEARCH, 1992, 12 (1-3) :131-139

[9] EXPRESSION OF THE OXYTOCIN AND VASOPRESSIN GENES IN THE RAT HYPOTHALAMUS DURING DEVELOPMENT - AN INSITU HYBRIDIZATION STUDY [J].

LAURENT, FM ;

HINDELANG, C ;

KLEIN, MJ ;

STOECKEL, ME ;

FELIX, JM .

DEVELOPMENTAL BRAIN RESEARCH, 1989, 46 (01) :145-154

[10] RAT STRIATAL AND MESENCEPHALIC NEURONS CONTAIN THE LONG ISOFORM OF THE D2 DOPAMINE RECEPTOR MESSENGER-RNA [J].

LEMOINE, C ;

BLOCH, B .

MOLECULAR BRAIN RESEARCH, 1991, 10 (04) :283-289

← 1 2 →