SOS MUTAGENESIS

被引：45

作者：

MURLI, S ^{[1
]}

WALKER, GC ^{[1
]}

机构：

[1] MIT, CAMBRIDGE, MA 02139 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(05)80089-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In Esherichia coli, UV and many chemicals appear to cause mutagenesis by a process of translesion synthesis that requires some form of DNA polymerase III and the SOS-regulated proteins UmuD, UmuC and RecA. An analysis of SOS mutagenesis offers insights into the molecular basis of induced mutagenesis and into mechanisms of DNA damage tolerance.

引用

收藏

页码：719 / 725

页数：7

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