TREATMENT OF POSTANOXIC INTENTION MYOCLONUS WITH VALPROIC ACID

被引：16

作者：

BRUNI, J

WILLMORE, LJ

WILDER, BJ

机构：

[1] VET ADM HOSP,NEUROL SERV,GAINESVILLE,FL 32602

[2] UNIV FLORIDA,COLL MED,DEPT NEUROL,GAINESVILLE,FL 32611

来源：

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES | 1979年 / 6卷 / 01期

关键词：

D O I：

10.1017/S0317167100119341

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Valproic acid in therapeutic doses was used in the treatment of postanoxic intention myoclonus. Disappearance of the myoclonus occurred with marked improvement in the electroencephalogram. No significant side effects were noted. Hepatic function tests were monitored. Determination of valproic acid plasma levels was used to guide therapy. Levels above 55 ßg were generally required. The patient remains free of myoclonus after four and one half months. © 1979, Canadian Neurological Sciences Federation. All rights reserved.

引用

页码：39 / 42

页数：4

共 28 条

[1]

BEDARD, 1974, LANCET, V1, P738

[2]

BOURDOURESQUES J, 1971, REV NEUROL PARIS, V125, P306

[3]

BRUNI J, 1978, CLIN PHARMACOL THER, V24, P324

[4]

BRUNI J, J CLIN PHARMACOL THE