RENIN INHIBITORS - DIPEPTIDE ANALOGS OF ANGIOTENSINOGEN UTILIZING A DIHYDROXYETHYLENE TRANSITION-STATE MIMIC AT THE SCISSILE BOND TO IMPART GREATER INHIBITORY POTENCY

被引：89

作者：

LULY, JR

BAMAUNG, N

SODERQUIST, J

FUNG, AKL

STEIN, H

KLEINERT, HD

MARCOTTE, PA

EGAN, DA

BOPP, B

MERITS, I

BOLIS, G

GREER, J

PERUN, TJ

PLATTNER, JJ

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 12期

关键词：

D O I：

10.1021/jm00120a005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：2264 / 2276

页数：13

相关论文

共 47 条

[11] PURIFICATION OF HUMAN RENIN SUBSTRATE
DORER, FE
LENTZ, KE
KAHN, JR
LEVINE, M
SKEGGS, LT
[J]. ANALYTICAL BIOCHEMISTRY, 1978, 87 (01) : 11 - 18
[12] 2-OXAZOLIDONE FORMATION BY PYROLYSIS OF BETA-IODOCARBAMATES . A STEREOSELECTIVE REACTION
FOGLIA, TA
SWERN, D
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1969, 34 (06) : 1680 - &
[13] NUCLEAR MAGNETIC-RESONANCE STUDY OF STEREOISOMERIC 2-OXAZOLIDONE AND 2-PHENYL-2-OXAZOLINE DERIVATIVES OF ALPHA-AMINO-BETA-HYDROXY ACIDS
FUTAGAWA, S
INUI, T
SHIBA, T
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1973, 46 (10) : 3308 - 3310
[14] RENIN INHIBITORS
GREENLEE, WJ
[J]. PHARMACEUTICAL RESEARCH, 1987, 4 (05) : 364 - 374
[15] RENIN INHIBITORS
HABER, E
[J]. HYPERTENSION, 1986, 8 (12) : 1093 - 1095
[16] DIPEPTIDE GLYCOLS - A NEW CLASS OF RENIN INHIBITORS
HANSON, GJ
BARAN, JS
LINDBERG, T
WALSH, GM
PAPAIOANNOU, SE
BABLER, M
BITTNER, SE
YANG, PC
DALCOROBBO, M
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 132 (01) : 155 - 161
[17] ENHANCED POTENCY DIPEPTIDE GLYCOL RENIN INHIBITORS - STUDIES INVITRO AND IN THE CONSCIOUS RHESUS
HANSON, GJ
BARAN, JS
LOWRIE, HS
SARUSSI, SJ
YANG, PC
BABLER, M
BITTNER, SE
PAPAIOANNOU, SE
WALSH, GM
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 146 (03) : 959 - 963
[18] RENIN INHIBITORS BASED ON NOVEL DIPEPTIDE ANALOGS - INCORPORATION OF THE DEHYDROHYDROXYETHYLENE ISOSTERE AT THE SCISSILE BOND
KEMPF, DJ
DELARA, E
STEIN, HH
COHEN, J
PLATTNER, JJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (11) : 1978 - 1983
[19] RENIN INHIBITORS - IMPROVEMENTS IN THE STABILITY AND BIOLOGICAL-ACTIVITY OF SMALL PEPTIDES CONTAINING NOVEL LEU-VAL REPLACEMENTS
KLEINERT, HD
LULY, JR
MARCOTTE, PA
PERUN, TJ
PLATTNER, JJ
STEIN, H
[J]. FEBS LETTERS, 1988, 230 (1-2) : 38 - 42
[20] EFFECTS OF THE RENIN INHIBITOR A-64662 IN MONKEYS AND RATS WITH VARYING BASELINE PLASMA-RENIN ACTIVITY
KLEINERT, HD
MARTIN, D
CHEKAL, MA
KADAM, J
LULY, JR
PLATTNER, JJ
PERUN, TJ
LUTHER, RR
[J]. HYPERTENSION, 1988, 11 (06) : 613 - 619

← 1 2 3 4 5 →