ELECTROCHEMICAL OXIDATION OF DNA AT A GOLD MICROELECTRODE

被引：56

作者：

PANG, DW ^{[1
]}

QI, YP ^{[1
]}

WANG, ZL ^{[1
]}

CHENG, JK ^{[1
]}

WANG, JW ^{[1
]}

机构：

[1] WUHAN UNIV,DEPT CHEM,WUHAN 430072,PEOPLES R CHINA

来源：

ELECTROANALYSIS | 1995年 / 7卷 / 08期

关键词：

DNA; ELECTROOXIDATION; GOLD ELECTRODE;

D O I：

10.1002/elan.1140070817

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The electrochemical oxidation of DNA at a gold microelectrode has been investigated using cyclic voltammetry with a homemade microliter cell. Denatured DNA is adsorbed and oxidized more easily at the gold electrode than native DNA. The electrochemical oxidation of DNA also depends on its strand length. The DNA oxidation product adsorbs strongly on the gold electrode, so poisoning and inactivating its surface; the adsorbed product also inhibits electrooxidation of the gold surface.

引用

页码：774 / 777

页数：4