HIGHER-ORDER NUCLEOPROTEIN COMPLEXES IN TRANSCRIPTION - ANALOGIES WITH SITE-SPECIFIC RECOMBINATION

被引：146

作者：

GROSSCHEDL, R ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO, HOWARD HUGHES MED INST, DEPT BIOCHEM, SAN FRANCISCO, CA 94143 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1995年 / 7卷 / 03期

关键词：

D O I：

10.1016/0955-0674(95)80091-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Regulation of transcription involves the assembly of multiprotein complexes at enhancers and promoters. interactions between adjacent and non-adjacent DNA-binding proteins can augment the specificity and stability of multicomponent nucleoprotein complexes. Recently, several proteins have been identified that can function as 'architectural' elements in the assembly of higher-order nucleoprotein structures reminiscent of those involved in site-specific recombination in prokaryotes.

引用

页码：362 / 370

页数：9

共 79 条

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