LONG-CIRCULATING IRON-OXIDES FOR MR-IMAGING

被引:342
作者
WEISSLEDER, R [1 ]
BOGDANOV, A [1 ]
NEUWELT, EA [1 ]
PAPISOV, M [1 ]
机构
[1] OREGON HLTH SCI UNIV, BLOOD BRAIN BARRIER PROGRAM, PORTLAND, OR 97201 USA
关键词
IRON OXIDE; MR IMAGING;
D O I
10.1016/0169-409X(95)00033-4
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
A variety of iron oxide preparations with long blood half-lives have been synthesized for MR imaging. Potential applications of these agents include MR angiography, RES imaging, target specific imaging and neuronal transport imaging. This chapter reviews types of iron oxide and mechanisms that are responsible for a prolonged plasma half-life.
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页码:321 / 334
页数:14
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