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NUCLEAR MICROSCOPY - ITS ROLE AND FUTURE IN MEDICINE AND TRACE-ELEMENT BIOLOGY

被引：15
作者：
LINDH, U
机构：
[1] Department of Radiation Sciences, Division of Physical Biology, Uppsala University, S-751 21 Uppsala
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 1991年 / 54卷 / 1-3期
基金：
加拿大自然科学与工程研究理事会;
关键词：
D O I：
10.1016/0168-583X(91)95507-A
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
Technological improvement has occurred for micron and submicron nuclear probes. However, the nuclear microprobe has not yet been fully appreciated in the medical society. Some examples of recent applications in neurotoxicology and immunotoxicology will be presented. Specimen preparation is a crucial step before subjecting samples to nuclear microprobe analysis. Different ways of maintaining specimen integrity will be discussed. Although being consuming, nuclear microprobe analyses often present a huge data set, and sometimes unexpected results are obtained. The scanning nuclear microprobes rapidly approach the practical resolution of electron microprobes with far better analytical sensitivity. Therefore, the adequate use of the technique at all levels of spatial resolution has to be discussed.
引用
收藏
页码：160 / 170
页数：11
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