ENANTIOSELECTIVE PROTONATION OF A SIMPLE ENOL - AMINOALCOHOL-CATALYZED KETONIZATION OF A PHOTOCHEMICALLY PRODUCED 2-METHYLINDEN-3-OL

被引：48

作者：

HENIN, F ^{[1
]}

MUZART, J ^{[1
]}

PETE, JP ^{[1
]}

MBOUNGOUMPASSI, A ^{[1
]}

RAU, H ^{[1
]}

机构：

[1] UNIV HOHENHEIM,FACHGEBIET PHYS CHEM,W-7000 STUTTGART 70,GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1991年 / 30卷 / 04期

关键词：

D O I：

10.1002/anie.199104161

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The enol 2, produced by a Norrish type II photoelimination from 1, is protonated enantioselectively to ketone 3 in the presence of (-)-ephedrine. Best optical yields are obtained at 0-degrees-C using small amounts of the chiral aminoalcohol. There is still wide scope for optimization.

引用

页码：416 / 418

页数：3