SYMPTOMATIC MANGANESE NEUROTOXICITY IN A PATIENT WITH CHRONIC LIVER-DISEASE - CORRELATION OF CLINICAL SYMPTOMS WITH MRI FINDINGS

被引：36

作者：

BARRON, TF

DEVENYI, AG

MAMOURIAN, AC

机构：

[1] MILTON S HERSHEY MED CTR,DEPT PEDIAT,DIV GASTROENTEROL,HERSHEY,PA 17033

[2] MILTON S HERSHEY MED CTR,DEPT RADIOL,HERSHEY,PA 17033

[3] PENN STATE UNIV,COLL MED,HERSHEY,PA

来源：

PEDIATRIC NEUROLOGY | 1994年 / 10卷 / 02期

关键词：

D O I：

10.1016/0887-8994(94)90047-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Hyperintense symmetric pallidal lesions have been described in chronic hepatic failure. Similar lesions are reported in experimental models of manganese neurotoxicity. We describe an 8-year-old girl with chronic hepatic failure and dystonia in association with an elevated whole blood manganese level and symmetric hyperintense pallidal lesions on magnetic resonance imaging. After hepatic transplantation, her symptoms and signs resolved with normalization of magnetic resonance imaging and the whole blood manganese suggesting that in chronic hepatic failure, the pallidal lesions may be secondary to manganese deposition.

引用

页码：145 / 148

页数：4

共 24 条

[11] CHRONIC ENTERAL POISONING CAUSED BY POTASSIUM-PERMANGANATE - A CASE-REPORT [J].