CRYSTALLIZATION AND PRELIMINARY-X-RAY DIFFRACTION ANALYSIS OF THE BETA-CHAIN OF A T-CELL ANTIGEN RECEPTOR

被引：13

作者：

BOULOT, G

BENTLEY, GA

KARJALAINEN, K

MARIUZZA, RA

机构：

[1] INST PASTEUR,CNRS,URA 359,F-75724 PARIS 15,FRANCE

[2] BASEL INST IMMUNOL,CH-4005 BASEL,SWITZERLAND

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1994年 / 235卷 / 02期

关键词：

T-CELL RECEPTOR; BETA-CHAIN; CRYSTALLIZATION; X-RAY ANALYSIS;

D O I：

10.1006/jmbi.1994.1037

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A secreted form of the β-chain of a T-cell receptor specific for a hemagglutinin peptide of influenza virus in the context of the major histocompatibility complex class II I-Ed molecule has been crystallized in a form suitable for X-ray diffraction analysis. The crystals are tetragonal, space group P41212 (or P43212), with cell dimensions a = b = 71.4 å, c = 312.9 å, and diffract to beyond 3.5 å resolution. The β-chain appears to behave as a stable homodimer in solution. © 1994 Academic Press Limited.

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页码：795 / 797

页数：3

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