SPLENIC HEMANGIOMA WITH THROMBOCYTOPENIA AND AFIBRINOGENEMIA

被引：39

作者：

THATCHER, LG

CLATANOFF, DV

STIEHM, ER

机构：

[1] Department of Pediatrics, University of Wisconsin Medical School, Madison, WI

[2] Department of Medicine, University of Wisconsin MedicalSchool, Madison, WI

来源：

JOURNAL OF PEDIATRICS | 1968年 / 73卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0022-3476(68)80111-8

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A 16-month-old boy who presented with bruising, anemia, an abdominal mass, thrombocytopenia, and afibrinogenemia was cured by the surgical removal of a large splenic hemangioma. Preoperatively, coagulation studies revealed low normal levels of Factors V and VIII, normal fibrinolysis, and high levels of immunologically detectable split products of fibrinogen. The half-life of 131I-labeled fibrinogen was 36 hours preoperatively and 72 hours postoperatively. Thirteen other cases of hemangioma and thrombocytopenia (Kasabach-Merritt syndrome) associated with hypofibrinogenemia are reviewed. © 1968 The C. V. Mosby Company.

引用

页码：345 / +

页数：1