ORGANOMETALLIC REAGENTS IN ORGANIC-SYNTHESIS .5. ORGANOCUPRATE CONJUGATE ADDITION - ALDOL CONDENSATION SYNTHETIC PROCEDURE FOR SEQUENTIAL FORMATION OF 2 CARBON-CARBON BONDS

被引：56

作者：

HENG, KK ^{[1
]}

SMITH, RAJ ^{[1
]}

机构：

[1] UNIV OTAGO,DEPT CHEM,DUNEDIN,NEW ZEALAND

来源：

TETRAHEDRON | 1979年 / 35卷 / 03期

关键词：

D O I：

10.1016/0040-4020(79)80083-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enolates produced from the conjugate addition reaction of lithium dialkylcuprates with α,β- unsaturated ketones react with aldehydes in the presence of zinc chloride to give overall β-alkyl α-hydroxyalkyl addition to the original alkene. Reaction of these enolates with carbon dioxide and ethyl formate is also reported. © 1979.

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页码：425 / 435

页数：11

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