SEQUENCE COMPARISONS FOR A HEPATITIS-C VIRUS GENOME RNA ISOLATED FROM A PATIENT WITH LIVER-CIRRHOSIS

被引：27

作者：

HONDA, M ^{[1
]}

KANEKO, S ^{[1
]}

UNOURA, M ^{[1
]}

KOBAYASHI, K ^{[1
]}

MURAKAMI, S ^{[1
]}

机构：

[1] KANAZAWA UNIV,CANC RES INST,DEPT BIOPHYS,KANAZAWA,ISHIKAWA 920,JAPAN

来源：

GENE | 1992年 / 120卷 / 02期

关键词：

HEPATOCELLULAR CARCINOMA; DIVERSITY; EVOLUTION; CHRONIC HEPATITIS; RNA VIRUS; NON-A NON-B HEPATITIS;

D O I：

10.1016/0378-1119(92)90114-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The nucleotide (nt) sequence was determined for an isolate of hepatitis C virus (HCV) derived from cirrhotic tissue of a patient with hepatocellular carcinoma. The 9408-nt sequence (EMBL Acq. No. X61596) showed homology of 90.7-91.4% on the nt level, as compared to two Japanese isolates from patients with a high titer of serum transaminase, 78.4-78.8% to those obtained in the United States, and 65.0% to that from an asymptomatic Japanese carrier. The phylogenetic tree of the six isolates classified them into three groups.

引用

页码：317 / 318

页数：2

共 8 条

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