ENHANCED PRODUCTION OF RAT INTERLEUKIN-8 BY IN-VITRO AND IN-VIVO INFECTIONS WITH INFLUENZA-A NWS VIRUS

被引：22

作者：

OCHIAI, H

IKESUE, A

KUROKAWA, M

NAKAJIMA, K

NAKAGAWA, H

机构：

[1] TOYAMA MED & PHARMACEUT UNIV,FAC MED,DEPT VIROL,SUGITANI 2630,TOYAMA,TOYAMA 93001,JAPAN

[2] TOYAMA MED & PHARMACEUT UNIV,FAC PHARMACEUT SCI,TOYAMA,TOYAMA 93001,JAPAN

[3] NAGOYA CITY UNIV,SCH MED,DEPT VIROL,MIZUHO KU,NAGOYA,AICHI 467,JAPAN

来源：

JOURNAL OF VIROLOGY | 1993年 / 67卷 / 11期

关键词：

D O I：

10.1128/JVI.67.11.6811-6814.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We investigated the interleukin-8 (IL-8)-producing activity of influenza A NWS virus in cultured rat kidney NRK-52E cells and a rat influenza model. The production of rat IL-8 increased significantly in the virus-infected cells but not in UV-inactivated virus- or split-product-treated cells. The increase in IL-8 production could be detected in the bronchoalveolar lavage of infected rats. These data suggest that infectious virus has the potential to accelerate the production of IL-8 in cultured cells and in vivo in airway-lining cells.

引用

页码：6811 / 6814

页数：4

共 21 条

[1] POLYMORPHONUCLEAR LEUKOCYTE DYSFUNCTION DURING INFLUENZA-VIRUS INFECTION IN CHINCHILLAS
ABRAMSON, JS
GIEBINK, GS
MILLS, EL
QUIE, PG
[J]. JOURNAL OF INFECTIOUS DISEASES, 1981, 143 (06) : 836 - 845
[2] BECKER S, 1991, J IMMUNOL, V147, P4307
[3] FHOI AMK, 1992, FEBS LETT, V309, P327
[4] PROTECTIVE MECHANISMS AGAINST PULMONARY INFECTION WITH INFLUENZA-VIRUS .1. RELATIVE CONTRIBUTION OF POLYMORPHONUCLEAR LEUKOCYTES AND OF ALVEOLAR MACROPHAGES TO PROTECTION DURING THE EARLY PHASE OF INTRANASAL INFECTION
FUJISAWA, H
TSURU, S
TANIGUCHI, M
ZINNAKA, Y
NOMOTO, K
[J]. JOURNAL OF GENERAL VIROLOGY, 1987, 68 : 425 - 432
[5] INFLUENZA-A VIRUS AND THE NEUTROPHIL - A MODEL OF NATURAL IMMUNITY
HARTSHORN, KL
KARNAD, AB
TAUBER, AI
[J]. JOURNAL OF LEUKOCYTE BIOLOGY, 1990, 47 (02) : 176 - 186
[6] STIMULATION OF TUMOR-NECROSIS-FACTOR SECRETION BY PURIFIED INFLUENZA-VIRUS NEURAMINIDASE
HOUDE, M
ARORA, DJS
[J]. CELLULAR IMMUNOLOGY, 1990, 129 (01) : 104 - 111
[7] LEVEL OF NEUTROPHIL CHEMOTACTIC FACTOR CINC GRO, A MEMBER OF THE INTERLEUKIN-8 FAMILY, ASSOCIATED WITH LIPOPOLYSACCHARIDE-INDUCED INFLAMMATION IN RATS
IIDA, M
WATANABE, K
TSURUFUJI, M
TAKAISHI, K
IIZUKA, Y
TSURUFUJI, S
[J]. INFECTION AND IMMUNITY, 1992, 60 (04) : 1268 - 1272
[8] Lamb R.A., 1989, INFLUENZA VIRUSES, P1
[9] CHANGES IN THE LEVELS OF RAT INTERLEUKIN-8/CINC AND GELATINASE IN THE EXUDATE OF CARRAGEENAN-INDUCED INFLAMMATION IN RATS
NAKAGAWA, H
IKESUE, A
KATO, H
DEBUCHI, H
WATANABE, K
TSURUFUJI, S
NAGANAWA, M
MITAMURA, M
[J]. JOURNAL OF PHARMACOBIO-DYNAMICS, 1992, 15 (09): : 461 - 466
[10] ANTIBODY-MEDIATED GROWTH OF INFLUENZA A NWS VIRUS IN MACROPHAGELIKE CELL-LINE P388D1
OCHIAI, H
KUROKAWA, M
HAYASHI, K
NIWAYAMA, S
[J]. JOURNAL OF VIROLOGY, 1988, 62 (01) : 20 - 26

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