A FACILE SYNTHESIS OF DISUBSTITUTED 1,1-DIFLUORO-1-ALKENES VIA DOUBLE TRANSMETALATION OF 2,2-DIFLUOROVINYLBORANES

被引：39

作者：

ICHIKAWA, J ^{[1
]}

MINAMI, T ^{[1
]}

SONODA, T ^{[1
]}

KOBAYASHI, H ^{[1
]}

机构：

[1] KYUSHU UNIV,INST ADV MAT STUDY,KASUGA,FUKUOKA 816,JAPAN

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 26期

关键词：

DIFLUOROALKENE; DIFLUOROVINYLBORANE; TRANSMETALATION; COUPLING REACTION; PALLADIUM CATALYST;

D O I：

10.1016/S0040-4039(00)92012-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,2,2-Trifluoroethyl p-toluenesulfonate is treated with butyllithium and trialkylboranes successively to generate 1-alkyl-2,2-difluorovinylboranes, which couple with aryl iodides in the presence of cuprous iodide and palladium catalyst to afford 1,1-difluoro-1-alkenes in excellent yields.

引用

页码：3779 / 3782

页数：4

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