BIOFERROELECTRICITY: MODELING THE TRANSITIONS OF THE SODIUM CHANNEL

被引：13

作者：

Bystrov, Vladimir S. ^{[1
]}

Leuchtag, H. Richard ^{[2
]}

机构：

[1] Acad Sci Bussia, Pushchino Res Ctr, Inst Math Problems Biol, Pushchino 142292, Moscow Region, Russia

[2] Texas So Univ, Dept Biol, Houston, TX 77004 USA

来源：

FERROELECTRICS | 1994年 / 155卷

关键词：

D O I：

10.1080/00150199408007477

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A thermodynamic model for a phase transition in sodium channels between a ferroelectric "closed" phase and an ion-conducting "open" phase is discussed. This model implies Curie-Weiss behavior in the dielectric properties of excitable membranes, and this is consistent with data from squid axon. The question as to whether a ferroelectric phase as small as a macromolecule of 270 kD can exist is analyzed. A molecular interpretation of the transitions is given in terms of helix-coil transitions.

引用

页码：19 / 24

页数：6

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