A STEREOSELECTIVE ROUTE TO ENANTIOMERICALLY PURE MYOINOSITOL DERIVATIVES STARTING FROM D-MANNITOL

被引：56

作者：

CHIARA, JL

MARTINLOMAS, M

机构：

[1] Instituto de Química Orgánica General, CSIC, E-28006 Madrid

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 18期

关键词：

D O I：

10.1016/S0040-4039(00)76674-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A carbocyclization route to inositols starling from alditols has been developed involving as a key step a stereoselective intramolecular pinacol coupling of a 1,6-dialdehyde promoted by samarium diiodide. This route has been applied to the synthesis of enantiomerically pure myo-inositol derivatives using readily available D-mannitol as starting material

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页码：2969 / 2972

页数：4

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