INHIBITORY ACTIVITY OF PODOPHYLLOTOXIN AND MATAIRESINOL-DERIVATIVE LIGNANS ON THE ROOT-GROWTH OF BRASSICA-CAMPESTRIS

被引：11

作者：

ARIMOTO, M ^{[1
]}

MATSUURA, S ^{[1
]}

MURO, C ^{[1
]}

TSUJIBO, H ^{[1
]}

MATSUMURA, E ^{[1
]}

YAMAGUCHI, H ^{[1
]}

INAMORI, Y ^{[1
]}

机构：

[1] OSAKA UNIV PHARMACEUT SCI, MATSUBARA, OSAKA 580, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1994年 / 58卷 / 01期

关键词：

D O I：

10.1271/bbb.58.189

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

All the lignans tested in a bioassay with Brassica campestris L. subsp. rapa HOOK. fil. et ANDERS inhibited the root growth of this plant, except for deoxypicropodophyllin. The effects of functional groups in the molecule on the inhibitory activity of these compounds were studied. It is suggested that the methylenedioxyl group and the stereochemical configuration of the lactone junction of podophyllotoxin derivatives were closely related to the inhibitory activity. The O-methyl derivative of two hydroxyl groups of matairesinol greatly enhanced the inhibition of root growth in this plant.

引用

页码：189 / 190

页数：2