POINT MUTATIONS IN THE DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE GENE AS THE MOLECULAR-BASIS FOR PYRIMETHAMINE RESISTANCE IN PLASMODIUM-FALCIPARUM

被引：109

作者：

ZOLG, JW

PLITT, JR

CHEN, GX

PALMER, S

机构：

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 1989年 / 36卷 / 03期

关键词：

D O I：

10.1016/0166-6851(89)90173-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

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页码：253 / 262

页数：10

相关论文

共 27 条

[1] A CONVENIENT PROCEDURE FOR PURIFICATION OF THYMIDYLATE SYNTHASE FROM L1210-CELLS
BANERJEE, CK
BENNETT, LL
BROCKMAN, RW
SANI, BP
TEMPLE, C
[J]. ANALYTICAL BIOCHEMISTRY, 1982, 121 (02) : 275 - 280
[2] PLASMODIUM-FALCIPARUM - INDUCTION, SELECTION, AND CHARACTERIZATION OF PYRIMETHAMINE-RESISTANT MUTANTS
BANYAL, HS
INSELBURG, J
[J]. EXPERIMENTAL PARASITOLOGY, 1986, 62 (01) : 61 - 70
[3] Blakley R. L., 1984, FOLATES PTERINES, P191
[4] MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF THE PLASMODIUM-FALCIPARUM DIHYDROFOLATE-REDUCTASE THYMIDYLATE SYNTHASE GENE
BZIK, DJ
LI, WB
HORII, T
INSELBURG, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (23) : 8360 - 8364
[5] CHEN GX, 1987, MOL PHARMACOL, V31, P430
[6] CHEN GX, 1987, MOL PHARMACOL, V32, P723
[7] CLEVELAND DW, 1977, J BIOL CHEM, V252, P1102
[8] AMINO-ACID CHANGES LINKED TO PYRIMETHAMINE RESISTANCE IN THE DIHYDROFOLATE-REDUCTASE THYMIDYLATE SYNTHASE GENE OF PLASMODIUM-FALCIPARUM
COWMAN, AF
MORRY, MJ
BIGGS, BA
CROSS, GAM
FOOTE, SJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (23) : 9109 - 9113
[9] THE MECHANISM OF PYRIMETHAMINE RESISTANCE IN PLASMODIUM-FALCIPARUM
DIECKMANN, A
JUNG, A
[J]. PARASITOLOGY, 1986, 93 : 275 - 278
[10] A BIFUNCTIONAL THYMIDYLATE SYNTHETASE-DIHYDROFOLATE REDUCTASE IN PROTOZOA
GARRETT, CE
CODERRE, JA
MEEK, TD
GARVEY, EP
CLAMAN, DM
BEVERLEY, SM
SANTI, DV
[J]. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1984, 11 (APR) : 257 - 265